A COMPARATIVE STUDY ON THE EFFICACY OF KUMKUMA NASYA AND GO-GHRITA NASYA IN THE MANAGEMENT OF ARDHAVABHEDAKA WITH SPECIAL REFERENCE TO MIGRAINE

Abstract

Introduction: Ardhavabhedaka have predominance of vata and vatakaphaja, Tridoshaja, vataja according to Acharya Charaka, Acharya Sushruta, and Acharya Vagbhatta respectively. The causes of ardhavabhedaka are excessive intake of rooksha padartha, Adhyashana, Purva-vata-sevana, Atimaithuna, Vegadharana, Ativyayama. Due to nidana- sevana vata-dosha get aggravated and pain is appreciable in Manya, Bhru, Shankha, Karna, Akshi and half of the Shirah. The attacks of ardhavabhedaka repeat every 10days, 15days, 30days or suddenly as per classical texts. As per modern view migraine is episodic headache. So, ardhavabhedaka can be correlated with migraine. Nasya is described as the best procedure in all Urdhwajatrugata rogas. In Chakradatta, Bhaishajyaratnavali had mentioned Go-ghrita nasya in the management of ardhavabhedaka. Also in Yogaratnakar, Chakradatta , Gadanigraha had described Kumkuma ghrita nasya in the management of ardhavabhedaka. Material and Methods: 30 cases of migraine diagnosed based on IHS Criteria were 15 patients were treated with kumkuma nasya and 15 patients were treated with go-ghrita nasya. The outcomes were assessed by standard scoring methods according to the symptoms of disease. Ethical clearance was obtained (PU/PIA/IECHR/2017/60) and this study is registered in Clinical Trial Registry of India (CTRI/2019/01/017208). Result: Effect of kumkuma nasya after treatment was highly significant in duration, frequency, severity of headache and vertigo. Also significant result was obtained in nausea, vomiting, photophobia, phonophobia. And non significant result was found in tinnitus and confusional state. Effect of go-ghrita nasya was highly significant in frequency of headache, severity of headache. Significant result was found in duration of headache, photophobia, vertigo, phonophobia. And non significant result was obtained in nausea, vomiting, tinnitus, confusional state. Discussion: The effect of Kumkuma nasya is better than effect of Go-ghrita nasya because kumkuma having a property of Vedanasthapana, Chardinigraha. Ghrita and Sharkara having property of Brimhana. And all drug having Tridoshashamaka property where Ardhavabhedaka have predominance of tridosha. Conclusion: According to statistical study, alternative hypothesis is accepted with percentage difference of 30.26% it can be concluded that the effect of kumkuma nasya is better than go-ghrita nasya in the management of ardhavabhedaka.