A CLINICAL STUDY ON THE MANAGEMENT OF PRATISHYAYA WITH PATOLADI SYRUP

Abstract

Introduction: According to Ayurveda “pratishanam shyayate iti pratishyayas” it means continuous outward movement of doshas. Pratishaya is one of the Vyadhi, which is characterized by Nasasrava, Nasavarodha, Shavathu, Shirashoola, Angamarda, Netrasrava and Netralalima. Acharya Sushrutha & Acharya Charaka explained that if Pratishyaya is not treated in time leads to dushta Pratishyaya associated with Shavas, Shotha, Kasa etc. This fact itself shows that Pratishyaya has been major problem to the physicians since long back. The Ingredients of Patoladi yoga are Patolpatra, Haritaki, Vibhitak and Amalaki which help in reducing Vata and Kapha doshas vitiation. Patients of pediatric age group don’t accept the dosage form of medicine ‘Kwatha’, ‘churna’ etc. So, taking the aspect of palatability with effective consideration the drug was administered in syrup form. Material and Methods: Fifty cases were assessed for pratishyaya. Thirty Five cases of pratishyaya were allocated for intervention. Five patients were lost to follow up. Thirty patients were analyzed for study with Patoladi syrup. The outcome were assessed by Changes in before treatment & after treatment assessment criteria Ethical clearance was obtained (PU/PIA/IECHR/2017/27) and this study is registered in Clinical Trial Registry of India (CTRI/2017/12/010932) Result: Severity of symptoms as assessed by before treatment & after treatment assessment criteria showed improvements in Shirashoola, Aruchi, Nasasrava, Nasaavrodh, Netrasrava, Netralalima, Angamarda, Shavathu which were statistically highly significant Effect of Patoladi syrup was statistically highly significant in management of pratishyaya Discussion: The effect of Patoladi syrup in Primary outcome measures in assessment criteria may be due to anti-oxidant, kaphahara & deepan-pachan which helps to prevent and reverse the pathogenesis. Conclusion: The Alternate hypothesis- Patoladi syrup is effective in the management of pratishyaya is accepted and Null hypothesis stands rejected.