Abstract:
Introduction: Kushtadi Churna is one of the classical formulations described in Chakradatta, Mukharoga adhikara which is used for problems related to tooth and gums. There is no research work has been carried out on the standardization and quality control aspects of Kushtadi Churna. In present scenario, people find it difficult for applying churna over the teeth as it is. So for better convenience and applicability, it has to be converted into a suitable dosage form. In the present study, an attempt was made to prepare an elegant Toothpaste from the already explained formulations in classics for pratisarana i.e. Kushtadi churna.
Aims & Objectives:
1. To convert Kushtadi Churna into Kusthadi Toothpaste.
2. To develop Standard Manufacturing Procedure of Kusthadi Churna & Kushtadi Toothpaste.
3. To develop possible analytical profile of Kushtadi Toothpaste.
Collection of raw materials
Kushta, Daruharidra, Lodhra, Mustha, Manjishta, Katuka, Patha, Tejani and Haridra; were procured from Pharmacy, Parul Institute of Ayurved, and was authenticated.
Material and Methods
It consists of three broad heading as
1. Conceptual study
2. Pharmaceutical study
3. Analytical study
Result:
After performing many trials and errors, a final composition of kushtadi toothpaste, which had good aroma, acceptable taste, elegancy and the criteria which was eligible for toothpaste formulation was made final for the rest of the study. The analytical study was carried out for both kushtadi churna and its toothpaste, were all within the range. The evaluation criteria for toothpaste was done and it showed good result and the HPTLC study, Anti-microbial study as well as Culture Sensitivity Test, the toothpaste had shown a good performance over the colony forming unit/ml over the oral bacteria’s.
Discussion –
Therefore it is seen that Kushtadi toothpaste is having certain therapeutic efficacy almost equivalent to Kushtadi Churna and there is much difference in Pharmaceutical and Analytical study of Kushtadi Churna and its toothpaste. The Kushtadi churna and toothpaste should be studied in detail for its Anti-Microbial with specific pathogens of oral region, also its stability studies and clinical efficacy.