A STUDY TO EVALUATE THE EFFECT OF GHRITPANA IN MANDAGNI

Abstract

INTRODUCTION: In Ayurveda the term “Agni” is used for the factor which performs the function of digestion of food and metabolism. Agni converts food in the form of energy, which is responsible for all vital functions of our body. In Sushruta Samhita, Mandagni is defined as Agni taking long time to digest even a very small quantity of consumed food and at the same time produces Udara shiro gaurava, Kasa, Shwasa, Praseka, Chhardi, Gatrasadana.Mandagni is the root cause of almost diseases. So, by maintaining Jatharagni in normal state, we can prevent further diseases. In view of this practical implementation of this study found to be possible and easily adaptable. Though Ayurveda had briefly explained the concept of Agni there is some lacuna in establishing the effect of Ghritpana in the victim of Mandagni. Deepan is aimed of correcting the Agni,by its regular use, life becomes healthy, Agni gets improved and health can be maintained. In all most Samhitas Go-Ghrita describe as Agnideepaka, but physician forgets the use of this Ghrita in the day-to-day practice. So, here, first Go-Ghrita was taken for the clinical study. AIM AND OBJECTIVES: • Aim:To evaluate the effect of Ghritpana in Mandagni. ABSTRACT • Objectives: 1. To evaluate Agni (Jatharagni). 2. To evaluate the effect of Ghritpana in Mandagni. METHODOLOGY: Clinical study was conducted on 50 subjects with the symptoms of having Mandagni condition. After getting Written consent from subject study was carried out and during this study 57 total subject were enrolled.All of them were clearly informed about study. 7 subjects quit treatment at different stage, hence only 50 subjects could complete Ghritpana treatment fully. The outcomes of subjective parameter were assessed by standard scoring method of Agnipareekshana patraka and objective parameter were assessed by BMR (Revised Harris Benedict Equation). Ethical clearance was obtained (PU/PIA/IECHR/2019/4) and this study is registered in Clinical Trial Registry of India (CTRI/2019/04/018468). OBSERVATIONS & RESULTS: Effect of Go-Ghrita was significant result in Abhyavaharana shakti, Jarana shakti,Udara-gaurava, Shiro gaurava and Gatrasadana. and not-significant result was obtained in Kasa. Overall effect of treatment- 50 subjects of Mandagni condition were treated by Go-Ghritpana. So, Go-Ghrita is the effective in the condition of Mandagni, which is statistically proven by improving in both the subjective and objective parameters, and also no recurrence was observed during the follow up period. During this study it has been observed that Agni produced by Go-Ghrita will stay for longer period So,Samagni Lakshana can be seen for long time. Go-Ghrita is having Madhura Rasa, Snigdha and Guru Guna,Sheeta Veerya. Go-Ghrita works efficiently with Prabhava and Agnideepana is effect of this. So, this Prabhava, work by suppressing Rasa, Vipaka and Veerya. CONCLUSION According to statistical study, the alternate hypothesis- Go-Ghrita has beneficial effect in Mandagni is accepted.