Abstract:
Peristrophe Bicalyculata have been reported to have many insecticidal and anti-bacterial
properties. For further investigation, the phytochemical, anti-microbial and anti-fungal
studies were carried out on the leaf part of the plant. This plant has been used in treating
various skin diseases. It is very useful in the treatment of T.B, Jaundice, Antiseptic and
Anti-venom agent in the traditional system of medicine. The screening indicates the
presence of various secondary metabolites such as tannins, alkaloids, flavonoids,
glycosides, terpenoids, reducing sugars and saponins. Ethanolic and aqueous extracts
were tested against five different microorganisms. Anti-fungal studies were carried out
against two fungi named Aspergillus Niger and Candida albicans. Anti-microbial as
well as anti-bacterial studies were carried out against Bacillus subtilis, Escherichia coli
and Staphylococcus Aureus. Anti-microbial activity was carried out at 100mg/ml
concentration by Agar Well Diffusion method. The evaluation revealed the ethanolic
extract was most effective against S.Aureus and Bacillus subtilis. No extract was active
against Aspergillus Niger. Ethanolic extracts were most effective in bacteria than fungi.
From the evaluation, the ethanolic extracts of Peristrophe Bicalyculata posses a good
source of various new drugs for treating various pathogens and infections.
