http://localhost:8080/xmlui/handle/123456789/8006 Fri, 10 Apr 2026 21:12:34 GMT 2026-04-10T21:12:34Z http://localhost:8080/xmlui/handle/123456789/8015 A COMPARETIVE ANALYTICAL STUDY OF MANDUKAPRNI (Centella asiatica Linn.) ACCORDING TO NAKASHATRA PATEL, DIPAL INTRODUCTION: The importance of Nakshatra and its effect on the body was very well understood and recognized by the ancient Indian scholars. The science of collection and use of medicinal plants at particular Nakshatra was a rich heritage of we Indians but it is on a verge of extinctions. Study on the behavior of the plant and their effect on the human body is the need of the hour. Moreover, when the world is looking at Ayurveda for better answers. Mandukparni (Centellaasiatica Linn.) is one of the best and commonly available herbs used as intellect promotors, memory enhancer and can cultivate with less efforts. Hence, the present study was taken up to collect the four sample in different Nakshatra and pharmacognostically compare it with A.P.I. METHODS: The plant materials were collected in four different Nakshatra -Bharani, Rohini, Mrigsirsha and Pushya. All the four sample of Mandukparni were subjected to Pharmacognostic evaluation which included Macroscopic and organoleptic evaluation, Microscopic evaluation, Physicochemical evaluation, Phytochemical evaluation and High-performance thin layer chromatography (HPTLC) as per standard method. OBERVATION AND RESULT: In the present study, macroscopic, organoleptic and microscopic evaluation of the four samples showed no marked difference. In Physicochemical evaluation, of the four samples showed values within the pharmacopeial limit.Phytochemical evaluation revealed the presence of carbohydrates,alkaloids, tannins,flavonoids,glycosides and steroids in all the samples. Sample3-MG (Mrigsirshanakshatra) showed the highest water soluble and alcohol soluble extractives and in the estimation of HPTLC evaluation sample 4(Pushya) (5/@254nm and 9/@366 nm),showed highest bends have been observed. DISCUSSION: Mandukparni(Centella asiatica Linn.) leaves taken out for the study and collected from the Pushya Nakshatrasample 4-PY (HPTLC) might be more potent and found better and superior result due to presence of more active principle based on the Pharmacognosticand Phytochemical study hence the study suggested CentellaasiaticaLinn. Leaves should be collected in Mrigsirshaand Pushya Nakshatrafor the therapeutic and medicinal use for the better results. Based on the findings the study also proposes that Mrigsirshaand Pushya Nakshatraalso influences the potency of drug. Hence the variation in this study is proves the change in chemical constituent this study also supports the old theories that Nakshatra has effect on plants as mentioned in Ayurvediclexicon. CONCLUSION: After evaluating the four samples in different Nakshatra, it is concluded that though the samples have macroscopic and microscopic similarity, variation exists in the Pushya and Mrigsirsha samples regarding its water soluble and alcohol soluble extractives, Judged from the qualitative and HTPLC study of Mandukparni.The study also supports the concept that the collection of medicinal plant shows variations in their activity depending upon their time of collection i.e. different Nakshatra. For Full Thesis Kindly contact to respective Library Mon, 01 Apr 2019 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/8015 2019-04-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/8013 COMPARATIVE EVALUATION OF SEASONAL SAMPLE OF ERANDAMOOLA (Ricinus communis Linn.) WITH SPECIAL REFERENCE (W.S.R) TO THEIR PHARMACOGNOSTICAL STUDYPHYTOCHEMISTRY Kumar, Sachin Comparative Evaluation Of Seasonal Sample Of Erandamoola (Ricinus Communis Linn) With Special Reference (W.S.R) To Their Pharmacognostical Study-Phyto-Chemistry. Ayurveda has many unique to well maintain health and cure the disease condition like herbs preparations. All medicinal plants from the major natural resources base of the Indian. Dravya Guna sangraha or collection of drug has been given importance in the study of dravya Guna shastra. The Dravya should be collected according to the principal or procedures laid down in Ayurveda. Acharya have been given indication of season, during which they should be collected and specified parts to be selected for medicinal purposes will contain more Virya- potentially or chemical active principles. In Ayurvedic literature, drug collection has been mentioned according to different parts of the plant in respective season. According to Ayurveda and modern science, drugs possess highest potentially during its collection period. The climate, rainfall, temperature, altitude, method of cultivation, duration of day light, collection of wild area, effect of lunar cycle and soil conditions. All affected the efficiency of the drug. METHODS: The plant material were collected from raw drug in three different season. All three samples of Eranda were subjected to pharmacognostic evaluation which included macroscopic and organoleptic evaluation, microscopic evaluation physicochemical evaluation, phytochemical evaluation and High performance thin layer chromatography as per standard methods. OBSERVATION AND RESULT In the present study, macroscopic, organoleptic and microscopic evaluation of the three different samples of Eranda moola showed no marked difference when compared to the samples except sample no 3 is different in colour. In physicochemical elevation, of the three samples, the three samples from different season presence values within the pharmacopeial limit. Phytochemical evaluation exposed the presence of Alkaloid, triterpenoids, tannin and carbohydrates in all three samples. HPTLC and quantitative values are different in all three samples. Discussion: The collection of root in different season is mention in samhita and nighantu. The study revealed similarity in macroscopic except (colour change in sample 3) and microscopic characters of all three samples physicochemical, quantitative and HPTLC evaluation of all samples shown that the sample no3 from the Shishira rtu to be good quality compared to other samples. Conclusion: after study the three samples (different season) comparing to each other the sample no 3 collected in Shishira rutu is found better because of the more extractive values (HPTLC) and low moisture content, high water soluble extractive values, maximum alkaloid and Tannin are also found in sample 3 (Shishira) shows more percentage because of the presence of more active principles. For Full Thesis Kindly contact to respective Library Mon, 01 Apr 2019 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/8013 2019-04-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/8011 AN ASSESSMENT OF VIRYA BY ENDOTHERMIC & EXOTHERMIC REACTION OF SELECTED DRUGS FROM ‘HARITAKYADI VARGA’ W.S.R. TO ‘BHAVPRAKASH NIGHANTU RATHOD, RAVIKUMAR Objectives: To assess shita virya dravya on the basis of endothermic reaction & ushna virya dravya by exothermic reaction. Then compare parameters obtained by test with virya mentioned in classical literature. Methodology: All 30 raw drug samples collected from ahmedabad market. Raw drug authentication was under raw drug authentication committee at Parul Institute of Ayurveda. Raw drugs samples are converted in to powder (Churna) form with following standard procedure in parul ayurvedic pharmacy. than experimental lab study started with 20 ml of Distilled water taken in a beaker and temperature were noted down for three time intervals (1 minute, 3 minutes and 5 minutes) after that 2 grams churna (powder) drug is added in Distilled water and stir it well with stirrer. Then again temperatures were noted down for three time intervals respectively. Changes of the temperature in 1 minute, 3 minutes and 5 minutes of intervals were noted down, Temperature will be analyzed by ‘External probe sensor digital thermometer’. Lab experiments of all 30 drugs are done at normal room temperature on day time. All above lab study done in Central Research Laboratory, Parul Institute of Ayurved. At the end of the lab study observation and result noted down. Results: Results obtained from observation shows that all 23 Usna Virya drugs like Haritaki, Vibhitaki, Shunthi, Maricha, Pippalimula, Chitraka, Yavani, Jiraka, Dhanyaka, Shatpushpa, Methika, Chandrika, Vacha, Vidanga, Kampillaka, Rasna, Sarpagandha, Katphal, Bharangi, Manjishtha, Haridra, Daru Haridra, Chakramarda respectively shows raise of temperature significantly. Results of observation shows all 6 Sita Virya Dravya drugs like Amalaki, Mishreya, Yastimadhu, Katukee, Dhataki, Lodhra respectively shows decrease of temperature followed by slight raise. In observation shows 1 Anusna dravya, Pippali shows significant raise of temperature. Conlusions: From the observation of present study it can be concluded that all the usna virya dravya showed exothermic reaction and rise in the temperature were noted down from given time intervals respectively. Same as shit virya dravya showed endothermic reaction and decrease the temperature were noted down from 3 time intervals respectively. Therefore the results parameters obtained by study are match with classical Ayurvedic reference and hypothesis is proved at end of study. Virya is having its own scope and application in the management of disease and clinical practice. Study revalidates estimation of virya of selected drug w.s.r. to Bhavaprakash Nighantu. For Full Thesis Kindly contact to respective Library Mon, 01 Apr 2019 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/8011 2019-04-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/8009 A COMPARATIVE PHARMACOGNOSTICAL AND PHYTOCHEMICAL STUDY OF CULTIVATED DANTI (Baliospermum montanum Muell. Arg.) AND ITS MARKET SAMPLES COLLECTED FROM GUJARAT VAIDYA, MINAL J. Introduction: Ayurveda has rich heritage of herbal preparations which are extensively used from continues with highly effective results; so whole the industry and intellect are concentrating towards it anxiously. But the deforestation and extinction of many species (biodiversity) and incorrect identification of many plants has been resulted in adulteration and substitution of raw drugs. To recover this factorneeded a major treat in the research on commercial natural products, like to promote the cultivation methods of the green plants. Aim: To evaluate and compare Pharmacognostic and Phytochemical properties of the cultivated sample (from Botanical Garden of Parul University) and market samples (from-Ahmedabad, Vadodara and Surat) of Dantimool (Baliospermum montanum Muell. Arg.’ roots) Objectives: • To collect drug - Dantimool (Baliospermum montanum Muell Arg.’s roots) samples from different markets of Gujarat (Ahmedabad, Vadodara and Surat) and cultivated variety from Botanical Garden of Parul University. • To study all the samples Pharmacognostically & Phytochemically. • To compare all the results with Ayurvedic Pharmacopoeia of India. Methodology: • The drug Danti-moolsamples were collected from three raw drug markets of Gujarat-Ahmedabad, Vadodara, Surat and also cultivated sample from Parul University Botanical Garden. • The drug was identified authentically at M S Uni, Botanical Department. • All the collected samples were studied Pharmacognostically & Analytically through API and other methods. • I.e. Microscopic, Ash values, Alkaloids,Water and Alcohol Soluble extractive etc. • HPTLC study was done for all the four samples of Drug Dantimool on three Rf values; 254nm, 366nm and 540nm. Results: • In the microscopic study, Sample PU 1 showed all the characters, which are the phloem, xylem, fibres, starch grains, vesells etc. Sample AM 2 and Sample VM 3 also showed the same characters with the presence of pith, while the Sample AM 2 and Sample SM 4 showed trichoms also. • The phytochemical study showed some differences in all samples. • The HPTLC study showed that ; • Maximum 11 peaks were in Samples PU 1 & AM 2 and minimum 3 peaks were in Samples AM 2, VM 3 & SM 4. • In all UV length total peaks of Sample PU 1 – 23, Sample AM 2 – 18, Sample VM 3 – 15 and Sample SM 4 – 13. • These result showed that the cultivated Sample PU 1 contain maximum chemicals in all four samples of Dantimool. Discussion: • All the results were compared with API for authenticity and also with each other. • The cultivated Sample PU 1 of Dantimool exactly matched with the API standard (Ayurvedic Pharmacopeia of India) at every aspect. • The market Sample AM 2 also matched with API and Sample PU 1 Parameters but it might be the stem portion of the drug Dantimool mixing with the root sample. • The market Sample VM 3 not exactly matched with Sample PU 1 and API, but it has some similarity with them. It might be some mixing of other substances with original drug sample of Dantimool. • The market Sample SM 4 does not match with API standard and not with the other samples of dantimool, it might be due to adulteration of the other drug. Conclusions: After analysing all samples of Dantimool, it can be concluded that; • The Sample of cultivated Dantimool has significant values in comparison to market Samples. • Due to adulteration, the market samples are not to be trusted some time blindly. • So for the therapeutic use of the raw drug, cultivated Dantimool has been more effective and Cultivation may be a good alternate or sourcefor herbal demand. It may be an alarm to save our endangered species. For Full Thesis Kindly contact to respective Library Mon, 01 Apr 2019 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/8009 2019-04-01T00:00:00Z