http://localhost:8080/xmlui/handle/123456789/7278 Fri, 10 Apr 2026 21:13:07 GMT 2026-04-10T21:13:07Z http://localhost:8080/xmlui/handle/123456789/7281 COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFECT OF KANASHATAHWADI KASHAYA GHANAVATI AND CAPSULE PCONIDD IN ARTAVKSHAYA W.S.R. TO PCOD Rathod, Shweta N. Introduction:PCOD is one of the most common endocrine disorders among women with reproductive age.Artavakshaya refers to irregularity of cycles in the form of oligomenorrhoea and hypomenorrhoea which are due to primary aggravation of Vata. Anartava is produced when Vatamarga is obstructed by Kapha. Due to this Vatamargaavrodha,there will be formation of Granthi. Based on this pathophysiology PCOD can be one of the leading cause for Artavakshaya.The present study included comparison between trial groups capsule Kanashatahwadi Kashaya and Capsule PCONIDD individually and combine for the management of Artavakshaya w.s.r to PCOD. Methodology: This study wasrandomized open comparative clinical study.Kanashatahwadi Kashayagranules were prepared in Pharmacy of PIA, Waghodia, Vadodara and filled in Dhanvantari pharmacy, Anand, Gujarat.Capsule PCONIDD procured from Snehanatura Pharmacy, Karnataka.Drug standardization and authentication was done before the clinical trial.30 patients fulfilling the diagnostic criteria were selected and randomly allocated in 3 groups of 10 each.The study duration was 3 months. The responses to the treatment as recorded and therapeutic effects were evaluated by symptomatic relief and through USG, S.LH, S.FSH hormone levels. Aim: To compare the effect of capsule Kanashatahwadi Kashayaand capsule PCONIDD and combine treatment protocol in PCOD. Objectives: 1. Comprehensive study of Artavakshaya with special reference to PCOD. 2. Comprehensive study of capsule Kanashatahwadi Kashayaand capsule PCONIDD and its therapeutic evaluation in PCOD. 3. To evaluate the effect of capsule Kanashatahwadi Kashayaand Capsule PCONIDD on reduction of cyst and decreasing ovarian volume. 4. To observe the effect of capsuleKanashatahwadi Kashayaand Capsule PCONIDD in regulation of menstrual cycle. Result:Total thirty seven patients were enrolled in study.Seven patients dropped out of the study and thirty patients completed the treatment. Total 10 patients completed the treatment in group A out of which maximum i.e. 50% moderate improved, 30% patients markedly improved and 20% patients reported mild improvement.None of patient reported unchanged and complete cured. Total 10 patients completed the treatment in group B out of which maximum i.e. 60%markedly improved, 30% patients moderate improved, 10% unchanged .None of patients reported mild improved and complete cured.Total 10 patients completed the treatment in group C out of which maximum i.e. 50% unchanged, 30% patients moderate improved, 20% markedly improved.None of patients reported mild improved and complete cured. Conclusion Today's lifestyle behavior like junk food habits, irregular dietary pattern and physical inactivity leads to menstrual irregularities related to PCOD especially in age group of 20-25 years. Guru, Atimadhuraaharasevana, Vishamashana, Anashana, Adhyashana, Diwaswapna, Ratrijagarana and Avyayama leads to Agnidushti, Dhatudushtiand further Artavahasrotodushti.. Capsule Kanashatahwadi Kashaya individually was found statistically significant in normalizing duration (45.5%)and interval of menstrual cycle(63.7%), improving the quantity of menstruation(81.8%), relieving the pain during menstruation(59.1%) and in reducing ovarian volume(57.3%).Capsule PCONIDD individually was found statistically significant in regularizing menstrual cycle (44.8%), improving the quantity of menstruation (55.0%), relieving pain during menstruation (59.9%), reducing ovarian volume (53.8%) and number of cysts (61.7%).Both combine capsules has significant result in regularizing menstrual cycle (61.2%), reducing ovarian volume (50.1%) For Full Thesis Kindly contact to respective Library Mon, 01 Jun 2020 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/7281 2020-06-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/7280 CLINICAL STUDY TO EVALUATE THE EFFECT OF MASANUMASIKA GARBHA SRAVA CHIKITSA IN PRECONCEPTIONAL CARE AND ANTENATAL CARE TO PREVENT GARBHA SRAVA W.S.R FIRST TRIMESTER ABORTION Kaur, Manpreet ABSTRACT –Women is a special creature of God as he has gifted woman with the ability to keep the human species alive via giving birth to new ones. Pregnancy period is grossly divided in three stages and are called trimesters. When women presents with subsequent pregnancy loss, it is frustrating and challenging problem for couples as well as clinicians. Garbha srava is often associated with guilt embarrassment and depressive state. More than 80% of abortions occur within the first 12 weeks of gestation. In present clinical study dravayas used for trial mentioned in Susruta Samhita , Astanga Sangrha , Harita Samhita , Yogaratnakara. Many preparations have been mentioned in ayurvedic texts for treatment and prevention of Garbhasthapaka, Garbhapaushaka ,Garbha srava , Garbha Raksha Vati is one of the modified formulation of churna to tablet form. AIM -To Evaluate the effect of Masanumasika Garbha Srava Chikitsa to prevent First Trimester Abortion. OBJECTIVE-Literary review of Garbha Srava and First Trimester Abortion , Literary review of Masanumasika Garbha Srava Chikitsa ,To compare the effects of Masanumasika Garbha Srava Chikitsa along with standard protocol for abortion management. METHODS- After the scrutiny , patients were registered in the study. Explained to the patient about the trial and effects of the drug. Written consent was taken in suitable language from the patient.INCLUSION CRITERIA-Married women with age 20-35 years,H/O spontaneous abortions in first trimester, H/O habitual abortion, C/O threatened abortion,Choriodecidual hemorrhage, UPT positive case with H/o of habitual abortion, Unexplained causes of abortion,Women with family history of recurrent abortion,Endocrine and metabolic like Thyroid dysfunction, Diabetes Mellitus. EXCLUSION CRITERIA-Women with H/o consanguineous marriage,Women age below 20 years above 35 years,Genetic causative factors for abortion, chromosomal abnormality,Anatomical abnormalities uterus,Immunological disorders. Number of patients registered for study were N=10 in group-1 i.e preconceptional trial group with garbha raksha vati -1st ,with Folic Acid , N=10 in group-2 i.e preconceptinal control group with Folic Acid ,N=32 in group-3 i.e. ANC trial group with Garbha Raksha Vati-2nd ,3rd & Folic Acid ,with P.O.G 4th -12th weeks , N=20 in group-4 i.e control group with Cap Progesterone & Folic Acid , with P.O.G 4th -12th weeks. RESULTS & CONCLUSION – In registered patients N=9 completed in group-1, N=10 completed in group -2 , N=32 completed in group-3 ,N=16 completed in group-4 in that 4 patients abortied during treatment. In preconceptional group-5.3% patients were concieved after one and half month of treatment, 36.8% patients were concived after two month of study duration. 86.5% ,patients continued the pregnancy thorough out 3 months with or without any complication , 5.8% had continue of pregnancy beyond 3 months with complications,7.7% patients were abortied in control group. Studying results of Garbha Raksha Vati groups during the treatment or after no abortion took place. The maternal as well as fetal growth was representing Garbhasthapaka, Garbhapaushaka Garbhavruddhikara prabhava which was prominently taken care by Garbha Raksha Vati For Full Thesis Kindly contact to respective Library Mon, 01 Jun 2020 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/7280 2020-06-01T00:00:00Z