http://localhost:8080/xmlui/handle/123456789/7262 2026-04-10T21:14:42Z http://localhost:8080/xmlui/handle/123456789/7268 A CLINICAL STUDY ON THE MANAGEMENT OF AMLAPITTA WITH WITH NARIKELA LAVANA Mamta, B INTRODUCTION: The Amlapitta is constituted of the words Amla and Pitta. The term Amla has been used as an appellation to Pitta. Though, the Amla has been said as natural property of Pitta along with Katu Rasa, according to Charaka. Sushruta has enlisted as its original rasa and mentioned that when the Pitta becomes Vidagdha, it transforms to Amla in Rasa By considering the disease as well as its symptoms, it seems that in Amlapitta, the Pitta seems distorted or is Vidagdha, as mentioned by Acharya Sushruta. Shrikantadatta in this commentary here, has defined that Amlapitta is a condition where excessive secretion of pitta with Amla in Guna takes place resulting in the condition like Vidaha, Tikta-Amlodgara etc. The review of Vedic Literature points to no known suggestive references regarding the description of Amlapitta. Eventually Acharya Charaka has not mentioned Amlapitta as a separate entity in the Samhita, while describing Grahaniroga, pathogenesis of Amlapitta has been clearly mentioned, while explaining the role of Agnidushti and its role in the manifestation of diseases by affecting the three Doshas, mainly the pitta. Madhava Nidana is the first text which describes its aetio-pathogenesis & symptoms. It classified Amlapitta into two clinical subtypes(i) Urdhwaghataamlapitta (ii) Adhoghataamlapitta). It also explained Lakshanas like Avipaka, Klama, Utklesha, Amlodgara, Hrt-kantaDaha, &Aruchi etc. Dyspepsia is defined by the ROME III committee on functional gastro-intestinal disorders as chronic or recurrent pain or discomfort centered in the upper abdomen. Discomfort means different things to different people but typically encompasses symptoms such as Bloating, Abdominal fullness, Early satiety and Nausea. It is an extremely common disorder in other- wise healthy population. Majority of patients however will be classified as having Non -Ulcer or Functional Dyspepsia. Prevalence of Functional Dyspepsia is about 20-30 % worldwide. A study from India reported to be 30.4%. The treatment option of recent origin described in American Journal of Gastroenterology is (i) test and treat for H. pylori using a validated non- invasive test and a trial of acid suppression. (ii) an empirical trial of acid suppression with a proton -pump inhibhitor is an initial option in a low prevalence area. Narikelalavanamentioned in Rasatarangini, indicated in Amlapitta. It is Laghu, Snighda, Sheetavirya, & Madhura vipaka. The present study aims to evaluate the general potential of oral administration of NarikelaLavanato prevent the progression of the disease and to relieve the symptoms. AIM: To carry out a Clinical Study on the Management of Amlapitta with NarikelaLavana. OBJECTIVES: Assessment of the clinical utility of Narikelalavana in Amlapitta as assessed by; Classical symptoms, GSRS Scale (Gastro-intestinal Symptom Rating scale) and QOLRAD Scale (Quality of Life in Reflux and Dyspepsia). METHODOLOGY: study design: open labelled clinical trial study selection: Patients suffering from amlapitta aged btween 20-50 years of either gender were taken in the study with chronicity of symptoms less than one month was selected from Parulayurved hospital, Vadodara. intervention: Patients treated with narikelalavana 1gms thrice daily before food with go ghrta for 14 days. RESULTS: The results were analysed before and after treatment based on assessment parameters, such as classical symptoms, GSRS Scale and QolRAD questionnaire using onw-way anova test. CONCLUSION: This study confirms that Narikelalavana is effective in Amlapitta. For Full Thesis Kindly contact to respective Library 2020-04-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/7266 A CLINICAL STUDY ON THE MANAGEMENT OF MUTRAKRICHCHRA WITH TRIKANTAKADYA GUGGULU DUBEY, PAYJANI The disease ‘Mutrakrichchra’ has cardinal feature of burningmicturation. Thus needs recognition to explore the newer therapeutic possibilities. It resembles Urinary Tract Infections in modern parlance which is major health problems affecting millions of people each year and frequent visits are seen in OPD in day to day practice. The present study is undertaken to evaluate the efficacy of TrikantakadayGuggulun in the management of Mutrakrichchra. to Urinary Tract Infections. METHODS Materials and Methods: Objective: To evaluate the therapeutic effect of TrikantakadyaGuggulu individually in patients suffering from Mutakrichchra. Design: It will be open labelled clinical study with pre and post-test design. Study selection: A 30patients suffering from Mutrakrichchra, irrespective of sex and caste will be selected from O.P.D. Kayachikitsa of Parul institute of Ayurevda hospital. Intervention: Selected patients were treated with “TrikantakadyaGuggulu” 1500 mg TDS for 14 days withAnupana Luke warm water. Main outcome measures: Based on the assessment criteria’s the parameters are graded and statistically analysed using Paired’ test RESULTS The overall effect of the therapies showed both the TrikantakadyaGuggulu having highly significant results in management of Mutrakrichchra. For Full Thesis Kindly contact to respective Library 2020-04-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/7264 A CLINICAL STUDY ON THE MANAGEMENT OF VATARAKTA WITH SPECIAL REFERENCE TO GOUT WITH NAVAKARSHIKA GHANA VATI Choube, Shivangi INTRODUCTION: Vatarakta is the disease which is having historical roots since Puranakala, is described in all the Samhitas and Samgraha Granthas with its details of Nidana Panchaka and Chikitsa as well. The incidence of Vatarakta still remains at peak as it emerges from inappropriate dietary regime, sedentary life style, occupation and environment. The disease is also known as Adhyavata which is self-explanatory that it is more prevalent among Adhya (Rich people). Vatarakta exhibits its resemblance with Gout disease described in modern parlance due to similarity in etiological factors, signs and symptoms. Gout is the most common cause of inflammatory arthritis in men aged more than 50, affecting approximately 1–2% of adult men in the Western world. Studies clarifies that urban Indian population is involved more than the rural population and due to increased prevalence of metabolic syndrome in younger population. Looking at the increasing epidemiology, the sources to eradicate the disease are always focused for management of the disease as well as to decrease the prevalence of disease. AIM AND OBJECTIVES: Aim: 1. To evaluate the therapeutic effect of Navakarshika Ghana Vati in the management of Vatarakta. Objectives: 1. To evaluate efficacy of Navakarshika Ghana Vati in reducing the serum uric acid level and classical symptoms of Gout. 2. To evaluate the adverse event of Navakarshika Ghana Vati if any. METHODOLOGY: Design: Open labeled .clinical study with pre and post design Study selection: 32 patients suffering from Vatarakta, irrespective of sex and caste were selected from O.P.D. Kayachikitsa of Parul institute of Ayurveda hospital. Intervention: Selected patients were treated with “Navakarshika Ghana Vati” 2 tab of 500mg four times a day for 2 months with Anupana of Luke warm water. OBSERVATIONS & RESULTS: Observations: Observations done during the study disclosed that maximum patients were from age group 51-60, female, had gradual onset & intermittent course, had movement as aggravating factor & rest as relieving factor, had positive family history, had association of great toe and knee joint each, had restricted range of motion of joints, had use of Madhura, Amla, Lavana Katu, Snigdha Ahara in their diet, were of Vata Pradhana Vatarakta, Gambhira Vatarakta, Intercritical gout and Samtarpana Janya Vatarakta, and reported with hyperuricemia. Results: Navakarshika Ghana Vati provided statistically highly significant result in subjective parameters viz. Sandhishula, Sandhishotha, Daha, Pain in small joints, Parvabheda, Stambha, interval of manifestation of symptoms and Visual Analog score whereas statistically significant result was found in Vaivarnya and Suptata. No result was on nodules of the Vatarakta patients. In objective parameters statistically highly significant result was obtained in reduction of Uric Acid, ESR and WBC. CONCLUSION: The study confirms that Navakarshika Ghana Vati selected for the study is effective in treating the disease. For Full Thesis Kindly contact to respective Library 2020-04-01T00:00:00Z