Faculty of Ayurveda

A CLINICAL STUDY ON THE EFFICAVY OF MANIBHADRA AVLEHA ALONG WITH MANSHEELADI OINTMENT IN THE MANAGEMENT OF SHWITRA.

2024-04-19T09:41:09Z

A CLINICAL STUDY ON THE EFFICAVY OF MANIBHADRA AVLEHA ALONG WITH MANSHEELADI OINTMENT IN THE MANAGEMENT OF SHWITRA. Shallu Sharma skin is the largest organ of our body, forming the oytermost surrounding layer. Normal skin color is dependent on hemoglobin, carotenoids and melanin pigment. Melanin pigment provides protection against UV rays. Melanocytes role is melanin synthesis. Leukoderma is an acquired loss of pigment in the skin which manifest itself by the occurrence of white patches usually surrounded bt normal or increased pigmentation. Shwitra is one of the common skin disorders which is correlated with leukoderma. Shwitra is a raktadustijanya vyadhi. Prevalence of vitiligo-Vitiligo is common in India, having a prevalence of 0.46 8.8%. Indian studies on childhood vitiligo have reported a prevalence of 2.6%.

An open label pilot study of kalyanaka ghrita in the management of obsessive compulsive disorder

2020-11-26T08:58:00Z

An open label pilot study of kalyanaka ghrita in the management of obsessive compulsive disorder RAJPUT, PURVI Background: Obsesseive and Compulsive Disorder or OCD is a heterogeneous and multidimensional disorder. The lifetime prevalence of OCD in general population is 2-3%. This is the fourth most common psychiatric diagnosis. It constitutes 10% of psychiatric OPD. The Standard or proven drug for the OCD is yet to explored in the field of Ayurveda, though few studies has been conducted but outcomes are not satisfactory. Objective: To evaluate the efficacy of Kalyanaka Ghrita in the management of Obsessive Compulsive Disorder. Method: Ethical clearance: Ethical clearance was obtained from Institutional Ethics Committee of Parul Institute of Ayurved, Parul University, Vadodara – 391760. Vide Ref- PIA/IECHR/2016-17/KC/04 dated 22/10/16. 10 patients of OCD satisfying the DSM-IV diagnostic criteria were selected. Kalyanaka Ghrita was administered to all for 60 days of period. The use of drug is in practice since very long, explained in Ayurvedic classics for various diseases, especially in Unmada. This drug was given for 60 days and patient then followed for one more month. There were total three assessments done before treatment, after treatment and after follow up. Yale Brown Obsessive Compulsive scale (Y-BOCS) was the selected for the measurement and Yale Brown Obsessive Compulsive symptoms checklist was selected to identify the symptoms. Results: Contamination Obsession, Symmetrical Obsession, Religious Obsession, Cleaning/Washing Compulsions, checking compulsions, Counting Compulsion, Ordering/Arranging Compulsions are the commonest symptoms of clinical presentation of OCD. Paired‘t’ test was used for statistical evaluation. 44.21% of relief was highly significant on reducing the symptoms of OCD on Y-BOCS (p<0.001). Interpretation: By understanding of Etiology, Symptomatology, Pathology, Course of Disease, Prognosis and Co-morbidity of OCD- the most suitable resemblance of OCD in Ayurveda is Grahonmada or Bhootonmada, no any other conditions. In present study it was found that almost every patients responded positively in short course of treatment and the positive effect the continued even after stopping the treatment in follow up period this may be because of long term and cumulative effect of the drug. After the complete follow up period the overall reduction of all symptoms was highly significant (about 44% reduction on Y-BOCS Score). This suggests Kalyanaka Ghrita is Highly Significant in the management of OCD. Conclusion: It is concluded that the efficacy of Kalyanaka Ghrita is statistically and clinically significant in the management of Obsessive Compulsive Disorder. For Full Thesis Kindly contact to respective Library

A clinical study on the management of diabetic polyneuropathy with rasayan vati

2020-11-26T08:54:37Z

A clinical study on the management of diabetic polyneuropathy with rasayan vati Kanase, Pallavi : Diabetic Polyneuropathy is one of the most common troublesome micro vascular complications of diabetes mellitus. It is nerve damaging disorders which are result in metabolic as well as vascular degeneration of neuron resulting in impaired nerve conduction. This neuropathy is leading independent risk factors (Hypertension, dyslipidemia, obesity, and cigarette smoking) for mortality and morbidity as a result of foot ulceration and non traumatic amputation of lower limb extremities. This makes the patient permanently immobile. In Ayurveda, although there is no direct correlation for Diabetic Polyneuropathy but the basic Most of the symptoms mentioned under purvaroopa and upadrava of Prameha such as pada daha, padasuptata, and shoola similar to diabetic Polyneuropathy symptoms. Pathology behind it is can be studied under madhumeha upadrava caused by Avarana janya vata prakopa. Hence in diabetics, prevention and management of Polyneuropathy is of utmost importance. This condition is well managed by Ayurveda with effectively and less cost. Materials and Methods: It is a clinical study with pre- test and post- test design conducted in single group. Rasayana Vati was given in a dose of 500mg 2 tablets twice in a daily for a period of 8 weeks. All the patients were followed up for a period of 4 week and assessment was done on the basis of subjective criteria (NSS and MNSI) and objective (Agni, Deha, Satwa bala and WHO QoL-BREF) criteria. Ethical clearance was obtained from Institutional Ethics Committee (IEC No. -PU/PIA/IECHR/KC/03), and this study is registered in Clinical Trial Registry of India (CTRI/2017/07/009075). Results : The change in the values before and after treatment were assessed by the paired‘t’ test. Statistically highly significant result was obtained in NSS (89.86%), MNSI-A (64.69%) and MNSI-B (71.69%). Discussion : Diabetic Polyneuropathy is a sequel to madhumeha which occurs due to further vitiation of doshas or due to vyadhi karshana. Diabetic Polyneuropathy is believed to occur due to Avrana janya vata prakopa. Vitiated vata damages nervous tissues by local inflammatory process (shoth) simultaneously Avrana causes sroto avrodh(obstruction in micro channels) which lead to malformation of preceding dhatu( progressive nutrition of tissues) leads to further dhatu kshya( emaciation at tissue level as well as at micro levels).which is produces symptoms like daha (burning sensation), suptata (numbness), harsha (tingling sensation), shosha (wasting), and dourbalya (weakness). This condition is well managed by Rasayana. Rasayan vati have property of Rasayana (Rejuvination), which act at the level of dhatu (body tissue), agni (metabolic activities), srotas (microcirculation). Rasayan vati contents anabhishyandi dravyas dominanted by singdha guna which acts as vata shaman, kapha-pitta avirodhi and srotoshodhana which clutches the samprapti of Avarana of vata. Conclusion : The hypothesis that the trial drug ‘Rasayana vati’ has beneficial effects on Diabetic Polyneuropathy is accepted and the null hypothesis is rejected. For Full Thesis Kindly contact to respective Library

A comparative study of agnikarma in the management of bahya arshas w.s.r to external skin tag.

2020-11-26T08:37:53Z

A comparative study of agnikarma in the management of bahya arshas w.s.r to external skin tag. SRINU, SHAH Introduction: Arshas is considered as one of the Asthat mahagada roga by Acharya Susruta for which different methods of management such as Bheshjakarma, ksharkarma, Shastrakarma Agnikarma and Raktamokshana. The approach of Agnikarma has been mentioned in the context of disease as Arsha, Arbuda, Bhagandar, Sira, Snayu, Asthi, Sandhigata Vata Vikaras etc.in which pain is a predominant symptom. Agnikarma can be ideate as ancient pain treatment tool . Arsha is an extremely common problem reported since many years with prevalence rate that is highest among all the anorectal disorders. But in Ayurveda four fold according to chronicity Agnikarma procedure seems to be more effective in clinical basis in the management of Arsha. Materials And Methods: It's an open randomized parallel trial group. A total 40 patients were selected randomly with the symptoms were divided in two groups, and in each group 20-20 patients were treated with Tamra shalaka and Panchadhatu shalaka. With those diseased group Exicsion of Bahya Arsha was done. Result: Both group had given remarkable improvement by the Agnikarma procedure which was carried out throughout the study. This shows that acts very well for the management of Arsha. Conclusion: Agnikarma by Tamra Shalaka gives better symptomatic relief than panchadhatu shalaka in the management of Bahya Arsha w.s.r to External skin tag. For Full Thesis Kindly contact to respective Library