Background: Bortezomib is a reversible inhibitor of proteasome proteins in mammalian cells. Bortezomib is proven to be cytotoxic to a number of tumor cells by disrupting their normal homeostatic mechanism and thereby, ...

Background: The clinical application of Brinzolamide, a drug used in the treatment of glaucoma is limited due its poor aqueous solubility. Microemulsion based ocular delivery can be an effective means to improve its ...

Background: Sickle cell disease (SCD) is an inherited disorder caused by a defect in the gene for hemoglobin. Patients can have one defective gene (sickle cell trait) or two defective genes (sickle cell disease) and globally ...